In discussion today someone mentioned that they would be curious to see the effect of a combination of anti-inflammatories such as omega-3 fatty acids and curcumin. I happened to be researching some more studies on curcumin and came across a study dealing with the prevention and treatment of pancreatic cancer with the use of curcumin and omega-3 fatty acids. The study was actually very interesting and is the first study done of its kind. Pancreatic adenocarcinoma is the fourth most common cause of cancer-related deaths and occurs in both men and women. It kills very quickly, patients usually die within 6 months of being diagnosed. Pancreatic cancer has upregulation of inflammation mediators suchs as those we have already discussed including nuclear factor kappa B, inductible nitric oxide synthase (iNOS), cycloxygenase-2 (COX-2) and 5-lipoinase (5-LOX). The study was done in vitro and in vivo models. This study shows that dietary administration of omega-3 fatty acids and curcumin suppresses the pancreatic tumor bettter than either one alone. The study overall shows many different things dealing with iNOS, COX-2, 5-LOX mediators. If you care to check out the study more I have provided the link to the article. I figured this article would tie in great with the omega-3 exercise article we discussed today in class.
Here is the link to the article:
http://www.informaworld.com.ezproxy1.library.arizona.edu/smpp/section?content=a905311628&fulltext=713240928
Subscribe to:
Post Comments (Atom)
2 comments:
I read this article that hot peppers could also been a natural alternative to COX inhibitor drugs. "Capsaicin" is the secret ingredient in hot peppers. This natural chemical is the secret ingredient that puts the "Hot" in hot peppers.
http://www.medicalnewstoday.com/articles/18269.php
I wonder how many other studies there are involving natural chemicals in different foods that we haven't discussed in class. Maybe we should stop using drugs to cure our problems and turn to certain types of foods.
I agree Lauren, but I think like we have mentioned in class that it comes down to having a balanced diet and having a variety of foods and spices. Many of the spices are dose dependent but are effective at a much higher dose than is found in foods. Alternative medicine does seem to be on the rise so its definitely something to look for.
Post a Comment